Revelo Lab

Welcome to the Revelo Lab!

Obesity-related inflammation of tissues such as the liver and visceral adipose tissue and liver is a key factor in the development of metabolic disease. In the liver, non-alcoholic fatty liver disease (NAFLD) is associated with hepatic insulin resistance and systemic glucose dysregulation. However, the immunological factors supporting these processes are poorly understood.

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Our research investigates the integrative biology of metabolic disease with emphasis on the role of the immune system on obesity and its complications. 

Follow us on twitter @Xavier_Revelo

 

We are currently hiring for highly motivated postdoctoral fellows. Please send a CV and short cover letter to Dr. Revelo xrevelo@umn.edu

Our laboratory aims to better understand the pathophysiology of non-alcoholic fatty liver disease or NAFLD which is estimated to affect 30% of the population. This is critical as NAFLD is one of the leading causes of abnormal liver function with no approved therapies for its treatment.

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Our current projects: 

    1. Mechanisms of hepatic and intestinal inflammation in obesity and NAFLD
    2. Anti-inflammatory mechanisms of exercise in obesity and NAFLD
    3. Modulation of immune pathways as potential therapeutics for metabolic disease

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